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段白露 讲师

发布时间:2023-10-07 点击量:

职称 讲师

学位 医学博士

邮箱 bailuduan2018(at)hbucm.edu.cn (发邮件时请将(at)换成@)

主要招生专业及方向

临床中药学 中药效用机理与临床应用研究

教育经历(从本科起倒序)

2014.09–2017.07,3044永利集团官网入口3044am永利集团,医学博士

2011.09–2014.07,3044永利集团官网入口中医临床学院,医学硕士

2006.09–2011.07,3044永利集团官网入口中医系,医学学士

主要工作经历(倒序)

2017.07–至今,3044永利集团官网入口3044am永利集团,讲师

科研方向

中药效用机理与临床应用研究

学术兼职

中华中医药学会中药基础理论分会青年委员

主要科研成果

主持项目(倒序)

1、湖北省教育厅指导性项目:基于HIF-1α/VEGF通路探讨茯苓-桂枝药对促心梗大鼠血管新生的作用机制及物质基础(B2021117),2021.01-2022.12,已结题;

2、3044永利集团官网入口“青苗计划”:基于JAK2/STAT3通路的糖康福散抗DPNP作用机制研究(2017ZZX011),2018.01至2020.05,已结题

代表性论著(#共同第一作者,*通讯作者

1. Hailing Huang, Bailu Duan*, Sili Zheng, Yan Ye, Dongning Zhang, Zhuang Huang, Shanshan Wang, Fengyun Zhang, Ping Huang, Fang Huang, Lintao Han*. Integrated network pharmacology and metabolomics analyses of the mechanism underlying the efficacy of Ma-Mu-Ran Antidiarrheal Capsules against dextran sulfate sodium-induced ulcerative colitis. Biomed Chromatogr, 2023, doi: 10.1002/bmc.5732.

2. Ping Huang #, Bailu Duan #, Deshun Li, Yanfen Duan, Zhenxiang Zhou, Lintao Han, Jingjing Li, Jiajia Wu, Yan Ye, Fengyun Zhang, Ziwen Guo, Qiong Wang*, Fang Huang*. Transcriptomics and metabolomics revealed the pulmonary protective mechanism of Xixin-Ganjiang Herb Pair for warming the lungs to dissolve phlegm in COPD rats. J Chromatogr B Analyt Technol Biomed Life Sci, 2023, doi: 10.1016/j.jchromb.2023.123665.

3. Sili Zheng, Dongning Zhang, Bailu Duan, Guoyan Mo, Jingjing Li, Hailing Huang , Shanshan Wang, Yan Ye, Zhuang Huang, Ping Huang, Fengyun Zhang, Fang Huang, Lintao Han. Metabolomics integrated network pharmacology reveals the mechanism of Ma-Mu-Ran Antidiarrheal Capsules on acute enteritis mice. Anal Biochem, 2023, doi: 10.1016/j.ab.2023.115116.

4. 叶焰,曾祥法,韩林涛,张风云,黄萍,郑思黎,张东宁,段艳芬,段白露*.基于UPLC-MS/MS和网络药理学探究茯苓-桂枝治疗心肌缺血的作用机制[J].世界科学技术-中医药现代化,2023,25(02):786-797.

5. Bailu Duan#, Yan Ye#, Zhenxiang Zhou, Lintao Han, Fang Huang, Jingjing Li, Qiong Wang, Xiangfa Zeng*, Xiaoming Yu*. Integrated Metabolomics and Network Pharmacology to Reveal the Mechanisms of Guizhi-Fuling Treatment for Myocardial Ischemia. Chem Biodivers, 2022,19(10):e202200386.

6. Fengyun Zhang, Bailu Duan*, Zhenxiang Zhou, Lintao Han, Ping Huang, Yan Ye, Qiong Wang, Fang Huang, Jingjing Li*. Integration of metabolomics and transcriptomics to reveal anti-chronic myocardial ischemia mechanism of Gualou Xiebai decoction. J Ethnopharmacol, 2022, doi: 10.1016/j.jep.2022.115530.

7. Dongning Zhang, Bailu Duan, Li Sun, Yanfen Duan, Sili Zheng, Jingjing Li , Hailong Yin, Dandan Mu, Shuaihong Hou, Guoyan Mo, Lintao Han, Fang Huang, Qiang Yin. Mechanism of Shiliu Buxue Syrup for anemia using integrated metabolomics and network pharmacology. Anal Biochem, 2022, doi: 10.1016/j.ab.2022.114774.

8. Ping Huang, Tao Huang, Deshun Li, Lintao Han, Zhenxiang Zhou, Fang Huang, Jingjing Li, Jiajia Wu, Yan Ye, Qiong Wang*, Bailu Duan*. Molecular Mechanism of Xixin-Ganjiang Herb Pair Treating Chronic Obstructive Pulmonary Disease-Integrated Network Pharmacology and Molecular Docking. Evid Based Complement Alternat Med, 2021, doi: 10.1155/2021/5532009.

9. Bailu Duan, Lintao Han, Shuping Ming, JingJing Li, Qiong Wang, Dongning Zhang, Guangyu Tian, Fang Huang. Fuling-Guizhi Herb Pair in Coronary Heart Disease: Integrating Network Pharmacology and In Vivo Pharmacological Evaluation. Evidence-Based Complementary and Alternative, 2020, doi: 10.1155/2020/1489036.

10. Sisi Liu, Xueting Liu, Hui Xiong, Wen Wang, Yutong Liu, Liang Yin, Chuyue Tu, Hua Wang, Xuechuan Xiang, Jinhong Xu, Bailu Duan, Ailin Tao, Zhongqiu Zhao, Zhinan Mei. CXCL13/CXCR5 signaling contributes to diabetes-induced tactile allodynia via activating pERK, pSTAT3, pAKT pathways and pro-inflammatory cytokines production in the spinal cord of male mice. Brain Behav Immun. 2019,80:711-724.

11. Bailu Duan, Zhongqiu Zhao, Weifang Liao, Hui Xiong, Sisi Liu, Liang Yin, Tiexiang Gao, Zhinan Mei. Tang-Kang-Fu-San in db/db Mice via Activation of PI3K/Akt and AMPK Pathways. Front Pharmacol, 2017, doi: 10.3389/fphar.2017.00535.

12. Bailu Duan, Zhongqiu Zhao, Ling Lin, Jing Jin, Lijun Zhang, Hui Xiong, Na Ta, Tiexiang Gao, Zhinan Mei. Antidiabetic Effect of Tibetan Medicine Tang-Kang-Fu-San on High-Fat Diet and Streptozotocin-Induced Type 2 Diabetic Rats. Evid Based Complement Alternat Med, 2017, doi: 10.1155/2017/7302965.

主讲课程(研究生,本科)

中药学(本科)

临床中药学(本科)